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Alzheimer's disease and dementia

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New hypothesis to explain Alzheimer’s disease and age-related dementia

A blood-clotting protein has been found to cause inflammation and synapse damage when it crosses the blood-brain barrier. View 1 Image. Source: Gladstone Institutes The field of Alzheimer's research is undoubtedly undergoing a difficult time right now. Rich Haridy. Rich is based in Melbourne, Australia and has strong interests in film, new media, and the new wave of psychedelic science. He has written for a number of online and print publications over the last decade while also acting as film critic for several radio broadcasters and podcasts. Sign in to post a comment.

ArneNormand February 7, PM. Have anyone tested Ethoxyquin as a possible culprit for helping to brake the brain-blood barrier? And norwegan research, banned and hidden by the breeders, have already proven that Ethoxyquin brakes this barrier, but further research has been stopped.

Signguy February 7, PM. Until we get rid of the toxin Fluoride that is forced upon the public by our own government even though it's been proven over and over to be dangerous to babies in the womb at the very least and all the carcinogenic chemicals used by Monsanto and others as well as Chemtrails in the air and the contamination from Fukishima that continues unabated to pollute our Waters and all of the creatures in the oceans all of this research is a distorted attempt that is doomed to fail.

WE are Killing Ourselves by "a thousand cuts". I have not read the study, as is only available to through subscription or purchase from Neuron. From what I have read here and in other summary articles, the mechanism described, in which fibrinogen leaks into the brain and sets off an immune response which destroys synaptic connections, operates independently of Alzheimer's disease. That is, a person with AD might have this problem as well, in which case the disease's progression would be accelerated; on the other hand, AD can exist and cause dementia without the presence of fibrinogen in the brain.

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It also seams reasonable that fibrinogen could leak into an otherwise unaffected brain and cause dementia on its own. If my assumptions are correct, I am unsure why the authors have tied their discovery so closely to Alzheimer's. Latest Stories. Anticancer compound shows promise in preclinical trials. Brain-controlled exoskeleton allows quadriplegic to walk and manipulate items. Fructose under fire, found to be worse on the liver than glucose. Skin patch measures antibiotic levels in real time. Bacteria caught changing shape to evade antibiotics.

Blood test reveals more than 20 types of cancer. Stanford study describes spice makers adding lead to turmeric. Numerous new treatments are being investigated in various stages of clinical trials. However, much can be offered to support and improve the lives of people with dementia and their carers and families. The principal goals for dementia care are:. Although age is the strongest known risk factor for dementia, it is not an inevitable consequence of ageing. Studies show that people can reduce their risk of dementia by getting regular exercise, not smoking, avoiding harmful use of alcohol, controlling their weight, eating a healthy diet, and maintaining healthy blood pressure, cholesterol and blood sugar levels, Additional risk factors include depression, low educational attainment, social isolation, and cognitive inactivity.

Dementia has significant social and economic implications in terms of direct medical and social care costs, and the costs of informal care. The total cost as a proportion of GDP varied from 0.

What is dementia?

Dementia can be overwhelming for the families of affected people and for their carers. Physical, emotional and financial pressures can cause great stress to families and carers, and support is required from the health, social, financial and legal systems.

People with dementia are frequently denied the basic rights and freedoms available to others. In many countries, physical and chemical restraints are used extensively in care homes for older people and in acute-care settings, even when regulations are in place to uphold the rights of people to freedom and choice. An appropriate and supportive legislative environment based on internationally-accepted human rights standards is required to ensure the highest quality of care for to people with dementia and their carers.

WHO recognizes dementia as a public health priority. In May , the World Health Assembly endorsed the Global action plan on the public health response to dementia The Plan provides a comprehensive blueprint for action — for policy-makers, international, regional and national partners, and WHO as in the following areas: addressing dementia as a public health priority; increasing awareness of dementia and establishing dementia-friendly initiatives; reducing the risk of dementia; diagnosis, treatment and care; information systems for dementia; support for dementia carers; and, research and innovation An international surveillance platform, the Global Dementia Observatory, has been established for policy-makers and researchers to facilitate monitoring and sharing of information on dementia policies, service delivery, epidemiology and research.

It can also be used for stakeholder mapping and priority setting.

What is Dementia and Alzheimer’s

Dementia is also one of the priority conditions in the WHO Mental Health Gap Action Programme mhGAP , which is a resource for generalists, particularly in low- and middle-income countries, to help them provide first-line care for mental, neurological and substance use disorders.

WHO has developed iSupport, a knowledge and skills training programme for carers of people living with dementia. Global action plan on the public health response to dementia - View publication. Cathy Greenblat.

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Dementia 19 September Key facts Dementia is a syndrome in which there is deterioration in memory, thinking, behaviour and the ability to perform everyday activities. Although dementia mainly affects older people, it is not a normal part of ageing. Worldwide, around 50 million people have dementia, and there are nearly 10 million new cases every year. Dementia has a physical, psychological, social, and economic impact, not only on people with dementia, but also on their carers, families and society at large.

Common symptoms include: forgetfulness losing track of the time becoming lost in familiar places. These include: becoming forgetful of recent events and people's names becoming lost at home having increasing difficulty with communication needing help with personal care experiencing behaviour changes, including wandering and repeated questioning. Symptoms include: becoming unaware of the time and place having difficulty recognizing relatives and friends having an increasing need for assisted self-care having difficulty walking experiencing behaviour changes that may escalate and include aggression.

Common forms of dementia There are many different forms of dementia. Treatment and care There is no treatment currently available to cure dementia or to alter its progressive course.